Insider filing report for Changes in Beneficial Ownership
- Schedule 13G & 13D forms are used to report a party's ownership of stock which exceeds 5% of a company's total stock issue.
- Schedule 13G is a shorter version of Schedule 13D with fewer reporting requirements.
"Insiders might sell their shares for any number of reasons, but they buy them for only one: they think the price will rise"
- Peter Lynch
What is insider trading>>
- Peter Lynch
What is insider trading>>
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of 1934
(Amendment No. 3)*
|
Syros Pharmaceuticals, Inc.
|
|
(Name of Issuer)
|
|
|
|
Common Stock
|
|
(Title of Class of Securities)
|
|
|
|
87184Q107
|
|
(CUSIP Number)
|
|
|
|
December 31, 2019
|
|
(Date of Event Which Requires Filing of this Statement)
|
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
☐ Rule 13d-1(b)
☐ Rule 13d-1(c)
☒ Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information
which would alter disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of
that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes).
|
CUSIP No. 87184Q107
|
13G
|
Page 2 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
ARCH Venture Fund VII, L.P.
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
Delaware
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
0
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
0
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.8%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
PN
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 3 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
ARCH Venture Partners VII, L.P.
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
Delaware
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
0
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
0
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.8%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
PN
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 4 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
ARCH Venture Partners VII, LLC
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
Delaware
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
0
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
0
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.8%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
OO
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 5 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
Keith Crandell
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
United States of America
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
27,953
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
27,953
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,341,770
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.9%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
IN
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 6 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
Clinton Bybee
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
United States of America
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
27,952
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
27,952
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,341,769
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.9%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
IN
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 7 of 12 Pages
|
|
1
|
NAMES OF REPORTING PERSONS
|
|
|
||
|
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
|
|
|
|||
|
Robert Nelsen
|
|
|
|||
|
|
|
||||
|
2
|
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||
|
(a)☐
|
|||||
|
(b)☐
|
|
|
|||
|
3
|
SEC USE ONLY
|
|
|
||
|
|
|
|
|||
|
|
|
||||
|
4
|
CITIZENSHIP OR PLACE OF ORGANIZATION
|
|
|
||
|
United States of America
|
|
|
|||
|
|
|
||||
|
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
|
5
|
SOLE VOTING POWER
|
|
|
|
|
27,953
|
|
|
|||
|
|
|
||||
|
6
|
SHARED VOTING POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
7
|
SOLE DISPOSITIVE POWER
|
|
|
||
|
27,953
|
|
|
|||
|
|
|
||||
|
8
|
SHARED DISPOSITIVE POWER
|
|
|
||
|
3,313,817
|
|
|
|||
|
|
|
||||
|
9
|
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
|
|
||
|
3,341,770
|
|
|
|||
|
|
|
||||
|
10
|
CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
|
|
|
||
|
☐
|
|
|
|||
|
|
|
||||
|
11
|
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
|
|
||
|
7.9%
|
|
|
|||
|
|
|
||||
|
12
|
TYPE OF REPORTING PERSON*
|
|
|
||
|
IN
|
|
|
|||
|
|
|
||||
|
CUSIP No. 87184Q107
|
13G
|
Page 8 of 12 Pages
|
| Item 1(a). | Name of Issuer |
Syros Pharmaceuticals, Inc. (the "Issuer").
| Item 1(b). | Address of Issuer's Principal Executive Offices |
35 CambridgePark Drive, Cambridge, MA 02140.
| Item 2(a). | Name of Person Filing |
ARCH Venture Fund VII, L.P. (“ARCH Venture Fund VII”); ARCH Venture Partners VII, L.P. (“AVP VII LP”); ARCH Venture Partners VII, LLC (“AVP VII LLC”) (collectively, the “Reporting Entities” and individually, each
a “Reporting Entity”); and Keith Crandell (“Crandell”), Robert Nelsen (“Nelsen”) and Clinton Bybee (“Bybee”) (collectively, the “Managing Directors” and individually, each a “Managing Director”). The Reporting Entities and the Managing
Directors collectively are referred to as the “Reporting Persons”.
| Item 2(b). | Address of Principal Business Office or, if none, Residence |
8755 W. Higgins Avenue, Suite 1025, Chicago, IL 60631
| Item 2(c). | Citizenship |
ARCH Venture Fund VII and AVP VII LP are limited partnerships organized under the laws of the State of Delaware. AVP VII LLC is a limited liability company organized under the laws of the State of Delaware. Each
Managing Director is a US citizen.
| Item 2(d). | Title of Class of Securities |
Common stock, par value $0.001 per share.
| Item 2(e). | CUSIP Number |
87184Q107
| Item 3. |
If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a:
|
Not Applicable.
| Item 4. | Ownership |
|
(a)
|
Amount beneficially owned:
|
ARCH Venture Fund VII is the record owner of 3,313,817 shares of Common Stock (the “Record Shares”) as of December 31, 2019. AVP VII LP, as the sole general partner of ARCH Venture Fund VII, may be deemed to
beneficially own the Record Shares. AVP VII LLC, as the sole general partner of AVP VII LP, may be deemed to beneficially own the Record Shares. As managing directors of AVP VII LLC, each Managing Director may also be deemed to share the
power to direct the disposition and vote of the Record Shares. In addition, as of December 31, 2019, Crandell is a holder of 27,953 Shares of Common Stock, Bybee is a holder of 27,952 shares of Common Stock, and Nelsen is the holder of 27,953
shares of Common Stock.
|
(b)
|
Percent of class:
|
See line 11 of the cover sheets. The percentages set forth on the cover sheet for each Reporting Person is based upon 42,441,227 shares of common stock outstanding as of October 31, 2019 as reported on the
Issuer’s Form 10-Q as filed with the Securities and Exchange Commission on November 12, 2019.
|
CUSIP No. 87184Q107
|
13G
|
Page 9 of 12 Pages
|
|
(c)
|
Number of shares as to which such person has:
|
(i) Sole power to vote or to direct the vote:
See line 5 of the cover sheets.
(ii) Shared power to vote or to direct the vote:
See line 6 of the cover sheets.
(iii) Sole power to dispose or to direct the disposition:
See line 7 of the cover sheets.
(iv) Shared power to dispose or to direct the disposition:
See line 8 of the cover sheets.
Each Reporting Person disclaims beneficial ownership of such shares of Common Stock except for the shares, if any, such Reporting Person holds of record.
| Item 5. | Ownership of Five Percent or Less of a Class |
Not Applicable.
| Item 6. | Ownership of More Than Five Percent on Behalf of Another Person |
Not Applicable.
| Item 7. |
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company
|
Not Applicable.
| Item 8. | Identification and Classification of Members of the Group |
Not Applicable.
| Item 9. | Notice of Dissolution of Group |
Not Applicable.
|
Item 10.
|
Certification
|
Not Applicable.
|
CUSIP No. 87184Q107
|
13G
|
Page 10 of 12 Pages
|
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Dated: February 13, 2020
|
ARCH VENTURE FUND VII, L.P.
|
|
|
By: ARCH Venture Partners VII, L.P.
|
|
| its General Partner |
|
By: ARCH Venture Partners VII, LLC
|
|
|
its General Partner
|
|
By: *
|
|
|
Keith Crandell
|
|
|
Managing Director
|
|
ARCH VENTURE PARTNERS VII, L.P.
|
|
|
By: ARCH Venture Partners VII, LLC
|
|
| its General Partner |
|
By: *
|
|
|
Keith Crandell
|
|
| Managing Director |
|
ARCH VENTURE PARTNERS VII, LLC
|
|
|
By: *
|
|
| Keith Crandell | |
| Managing Director |
|
*
|
|
| Keith Crandell |
|
*
|
|
|
Robert Nelsen
|
|
*
|
|
|
Clinton Bybee
|
|
* By: /s/ Mark McDonnell
|
||
|
Mark McDonnell as
|
||
|
Attorney-in-Fact
|
This Amendment No. 3 to Schedule 13G was executed by Mark McDonnell pursuant to Powers of Attorney attached hereto as Exhibit 2 and incorporated herein by reference.
|
CUSIP No. 87184Q107
|
13G
|
Page 11 of 12 Pages
|
Exhibit 1
AGREEMENT
Pursuant to Rule 13d-1-(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with
respect to the ownership by each of the undersigned of shares of stock of Syros Therapeutics, Inc.
This Agreement may be executed in any number of counterparts, each of which shall be deemed an original.
| Dated: February 13, 2020 |
ARCH VENTURE FUND VII, L.P.
|
|
By: ARCH Venture Partners VII, L.P.
|
|
| its General Partner |
|
By: ARCH Venture Partners VII, LLC
|
|
|
its General Partner
|
|
By: *
|
|
|
Keith Crandell
|
|
|
Managing Director
|
|
ARCH VENTURE PARTNERS VII, L.P.
|
|
|
By: ARCH Venture Partners VII, LLC
|
|
| its General Partner |
|
By: *
|
|
|
Keith Crandell
|
|
| Managing Director |
|
ARCH VENTURE PARTNERS VII, LLC
|
|
|
By: *
|
|
| Keith Crandell | |
| Managing Director |
|
*
|
|
| Keith Crandell |
|
*
|
|
|
Robert Nelsen
|
|
*
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Clinton Bybee
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* By: /s/ Mark McDonnell
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Mark McDonnell as
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Attorney-in-Fact
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This Agreement was executed by Mark McDonnell pursuant to Powers of Attorney attached hereto as Exhibit 2 and incorporated herein by reference.
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CUSIP No. 87184Q107
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13G
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Page 12 of 12 Pages
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Exhibit 2
POWERS OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below hereby constitutes and appoints Mark McDonnell his true and lawful attorney-in-fact, with full power of
substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable or appropriate to be executed on behalf of himself as an individual or in his capacity as a direct or indirect general partner, director,
officer or manager of any partnership, corporation or limited liability company, pursuant to section 13 or 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and any and all regulations promulgated thereunder, and to file
the same, with all exhibits thereto, and any other documents in connection therewith, with the Securities and Exchange Commission, and with any other entity when and if such is mandated by the Exchange Act or by the Financial Industry Regulatory
Authority, granting unto said attorney-in-fact full power and authority to do and perform each and every act and thing necessary, desirable or appropriate, fully to all intents and purposes as he might or could do in person, thereby ratifying and
confirming all that said attorney-in-fact, or his substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 7th day of May, 2013.
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ARCH VENTURE FUND VII, L.P.
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By: ARCH Venture Partners VII, L.P.
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| its General Partner |
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By: ARCH Venture Partners VII, LLC
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its General Partner
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By: /s/ Keith Crandell
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Managing Director
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ARCH VENTURE PARTNERS VII, L.P.
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By: ARCH Venture Partners VII, LLC
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| its General Partner |
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By: /s/ Keith Crandell
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| Managing Director |
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ARCH VENTURE PARTNERS VII, LLC
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By: /s/ Keith Crandell
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| Managing Director |
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/s/ Keith Crandell
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| Keith Crandell |
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/s/ Robert Nelsen
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Robert Nelsen
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/s/ Clinton Bybee
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Clinton Bybee
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