Insider filing report for Changes in Beneficial Ownership
- Schedule 13G & 13D forms are used to report a party's ownership of stock which exceeds 5% of a company's total stock issue.
- Schedule 13G is a shorter version of Schedule 13D with fewer reporting requirements.
- Peter Lynch
What is insider trading>>
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. )*
Milestone Pharmaceuticals Inc.
(Name of Issuer)
Common Shares, without par value
(Title of Class of Securities)
59935V107
(CUSIP Number)
September 9, 2022
(Date of Event Which Requires Filing of This Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
| ¨ | Rule 13d-1(b) |
| x | Rule 13d-1(c) |
| ¨ | Rule 13d-1(d) |
| * | The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. |
The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
| CUSIP No. 59935V107 | Page 2 of 13 |
| 1. |
Name of reporting persons
Venrock Healthcare Capital Partners III, L.P. | |||||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| |||||||
| 3. |
SEC USE ONLY
| |||||||
| 4. |
Citizenship or Place of Organization
Delaware | |||||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | ||||||
| 6. |
Shared Voting Power
2,072,0092 | |||||||
| 7. |
Sole Dispositive Power
0 | |||||||
| 8. |
Shared Dispositive Power
2,072,0092 | |||||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | |||||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| |||||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | |||||||
| 12. |
Type of Reporting Person (See Instructions)
PN | |||||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 3 of 13 |
| 1. |
Name of reporting persons
VHCP Co-Investment Holdings III, LLC | |||||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| |||||||
| 3. |
SEC USE ONLY
| |||||||
| 4. |
Citizenship or Place of Organization
Delaware | |||||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | ||||||
| 6. |
Shared Voting Power
2,072,0092 | |||||||
| 7. |
Sole Dispositive Power
0 | |||||||
| 8. |
Shared Dispositive Power
2,072,0092 | |||||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | |||||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| |||||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | |||||||
| 12. |
Type of Reporting Person (See Instructions)
OO | |||||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 4 of 13 |
| 1. |
Name of reporting persons
Venrock Healthcare Capital Partners EG, L.P. | |||||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| |||||||
| 3. |
SEC USE ONLY
| |||||||
| 4. |
Citizenship or Place of Organization
Delaware | |||||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | ||||||
| 6. |
Shared Voting Power
2,072,0092 | |||||||
| 7. |
Sole Dispositive Power
0 | |||||||
| 8. |
Shared Dispositive Power
2,072,0092 | |||||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | |||||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| |||||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | |||||||
| 12. |
Type of Reporting Person (See Instructions)
PN | |||||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 5 of 13 |
| 1. |
Name of reporting persons
VHCP Management III, LLC | |||||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| |||||||
| 3. |
SEC USE ONLY
| |||||||
| 4. |
Citizenship or Place of Organization
Delaware | |||||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | ||||||
| 6. |
Shared Voting Power
2,072,0092 | |||||||
| 7. |
Sole Dispositive Power
0 | |||||||
| 8. |
Shared Dispositive Power
2,072,0092 | |||||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | |||||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| |||||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | |||||||
| 12. |
Type of Reporting Person (See Instructions)
OO | |||||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 6 of 13 |
| 1. |
Name of reporting persons
VHCP Management EG, LLC | ||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| ||||
| 3. |
SEC USE ONLY
| ||||
| 4. |
Citizenship or Place of Organization
Delaware | ||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | |||
| 6. |
Shared Voting Power
2,072,0092 | ||||
| 7. |
Sole Dispositive Pow er
0 | ||||
| 8. |
Shared Dispositive Power
2,072,0092 | ||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | ||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| ||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | ||||
| 12. |
Type of Reporting Person (See Instructions)
OO | ||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 7 of 13 |
| 1. |
Name of Reporting Persons
Shah, Nimish | ||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| ||||
| 3. |
SEC USE ONLY
| ||||
| 4. |
Citizenship or Place of Organization
United States | ||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | |||
| 6. |
Shared Voting Power
2,072,0092 | ||||
| 7. |
Sole Dispositive Power
0 | ||||
| 8. |
Shared Dispositive Power
2,072,0092 | ||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | ||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| ||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | ||||
| 12. |
Type of Reporting Person (See Instructions)
IN | ||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 8 of 13 |
| 1. |
Name of Reporting Persons
Koh, Bong | ||||
| 2. |
Check the Appropriate Box if a Member of a Group (See Instructions) (a) x1 (b) ¨
| ||||
| 3. |
SEC USE ONLY
| ||||
| 4. |
Citizenship or Place of Organization
United States | ||||
|
Number of Shares Beneficially Owned by Each Reporting Person With: |
5. |
Sole Voting Power
0 | |||
| 6. |
Shared Voting Power
2,072,0092 | ||||
| 7. |
Sole Dispositive Power
0 | ||||
| 8. |
Shared Dispositive Power
2,072,0092 | ||||
| 9. |
Aggregate Amount Beneficially Owned by Each Reporting Person
2,072,0092 | ||||
| 10. |
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨
| ||||
| 11. |
Percent of Class Represented by Amount in Row (9)
6.9%3 | ||||
| 12. |
Type of Reporting Person (See Instructions)
IN | ||||
| 1 | Venrock Healthcare Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG, L.P., VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong Koh are members of a group for the purposes of this Schedule 13G. |
| 2 | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. |
| 3 | This percentage is calculated based upon 30,010,873 of the Issuer’s common shares outstanding as of August 10, 2022 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 10, 2022. |
| CUSIP No. 59935V107 | Page 9 of 13 |
Introductory Note: This Schedule 13G is filed on behalf of Venrock Healthcare Capital Partners III, L.P., a limited partnership organized under the laws of the State of Delaware (“VHCP III LP”), VHCP Co-Investment Holdings III, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Co-Investment III”), Venrock Healthcare Capital Partners EG, L.P., a limited partnership organized under the laws of the State of Delaware (“VHCP EG”), VHCP Management III, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Management III”), VHCP Management EG, LLC, a limited liability company organized under the laws of the State of Delaware (“VHCP Management EG” and collectively with VHCP III LP, VHCP Co-Investment III, VHCP EG and VHCP Management III, the “Venrock Entities”), Nimish Shah (“Shah”) and Bong Koh (“Koh”) in respect of Common Shares of Milestone Pharmaceuticals Inc.
Item 1.
| (a) | Name of Issuer |
Milestone Pharmaceuticals Inc.
| (b) | Address of Issuer’s Principal Executive Offices |
1111 Dr. Frederik-Philips Boulevard, Suite 420
Montréal, Québec Canada H4M 2X6
Item 2.
| (a) | Name of Person Filing |
Venrock Healthcare Capital Partners III, L.P.
VHCP Co-Investment Holdings III, LLC
Venrock Healthcare Capital Partners EG, L.P.
VHCP Management III, LLC
VHCP Management EG, LLC
Nimish Shah
Bong Koh
| (b) | Address of Principal Business Office or, if none, Residence |
| New York Office: | Palo Alto Office: | |
| 7 Bryant Park | 3340 Hillview Avenue | |
| 23rd Floor | Palo Alto, CA 94304 | |
| New York, NY 10018 |
| (c) | Citizenship |
All of the Venrock Entities were organized in Delaware. The individuals are both United States citizens.
| (d) | Title of Class of Securities |
Common Shares, without par value
| (e) | CUSIP Number |
59935V107
| CUSIP No. 59935V107 | Page 10 of 13 |
| Item 3. | If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a: |
Not applicable
| Item 4. | Ownership |
| (a) | Amount Beneficially Owned as of September 19, 2022: |
| Venrock Healthcare Capital Partners III, L.P. | 2,072,009 | (1) | ||
| VHCP Co-Investment Holdings III, LLC | 2,072,009 | (1) | ||
| Venrock Healthcare Capital Partners EG, L.P. | 2,072,009 | (1) | ||
| VHCP Management III, LLC | 2,072,009 | (1) | ||
| VHCP Management EG, LLC | 2,072,009 | (1) | ||
| Nimish Shah | 2,072,009 | (1) | ||
| Bong Koh | 2,072,009 | (1) |
| (b) | Percent of Class as of September 19, 2022: |
| Venrock Healthcare Capital Partners III, L.P. | 6.9 | % | ||
| VHCP Co-Investment Holdings III, LLC | 6.9 | % | ||
| Venrock Healthcare Capital Partners EG, L.P. | 6.9 | % | ||
| VHCP Management III, LLC | 6.9 | % | ||
| VHCP Management EG, LLC | 6.9 | % | ||
| Nimish Shah | 6.9 | % | ||
| Bong Koh | 6.9 | % |
| (c) | Number of shares as to which the person has, as of September 19, 2022: |
| (i) | Sole power to vote or to direct the vote |
| Venrock Healthcare Capital Partners III, L.P. | 0 | |||
| VHCP Co-Investment Holdings III, LLC | 0 | |||
| Venrock Healthcare Capital Partners EG, L.P. | 0 | |||
| VHCP Management III, LLC | 0 | |||
| VHCP Management EG, LLC | 0 | |||
| Nimish Shah | 0 | |||
| Bong Koh | 0 |
| (ii) | Shared power to vote or to direct the vote |
| Venrock Healthcare Capital Partners III, L.P. | 2,072,009 | (1) | ||
| VHCP Co-Investment Holdings III, LLC | 2,072,009 | (1) | ||
| Venrock Healthcare Capital Partners EG, L.P. | 2,072,009 | (1) | ||
| VHCP Management III, LLC | 2,072,009 | (1) | ||
| VHCP Management EG, LLC | 2,072,009 | (1) | ||
| Nimish Shah | 2,072,009 | (1) | ||
| Bong Koh | 2,072,009 | (1) |
| CUSIP No. 59935V107 | Page 11 of 13 |
| (iii) | Sole power to dispose or to direct the disposition of |
| Venrock Healthcare Capital Partners III, L.P. | 0 | |||
| VHCP Co-Investment Holdings III, LLC | 0 | |||
| Venrock Healthcare Capital Partners EG, L.P. | 0 | |||
| VHCP Management III, LLC | 0 | |||
| VHCP Management EG, LLC | 0 | |||
| Nimish Shah | 0 | |||
| Bong Koh | 0 |
| (iv) | Shared power to dispose or to direct the disposition of |
| Venrock Healthcare Capital Partners III, L.P. | 2,072,009 | (1) | ||
| VHCP Co-Investment Holdings III, LLC | 2,072,009 | (1) | ||
| Venrock Healthcare Capital Partners EG, L.P. | 2,072,009 | (1) | ||
| VHCP Management III, LLC | 2,072,009 | (1) | ||
| VHCP Management EG, LLC | 2,072,009 | (1) | ||
| Nimish Shah | 2,072,009 | (1) | ||
| Bong Koh | 2,072,009 | (1) |
| (1) | Consists of (i) 544,737 shares held by Venrock Healthcare Capital Partners III, L.P., (ii) 54,486 shares held by VHCP Co-Investment Holdings III, LLC and (iii) 1,472,786 shares held by Venrock Healthcare Capital Partners EG, L.P. VHCP Management III, LLC is the general partner of Venrock Healthcare Capital Partners III, L.P. and the manager of VHCP Co-Investment Holdings III, LLC. VHCP Management EG, LLC is the general partner of Venrock Healthcare Capital Partners EG, L.P. Messrs. Shah and Koh are the voting members of VHCP Management III, LLC and VHCP Management EG, LLC. |
| Item 5. | Ownership of Five Percent or Less of a Class |
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ¨.
| Item 6. | Ownership of More than Five Percent on Behalf of Another Person |
Not Applicable
| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. |
Not Applicable
| Item 8. | Identification and Classification of Members of the Group |
Not Applicable
| Item 9. | Notice of Dissolution of a Group |
Not Applicable
| Item 10. | Certification |
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
| CUSIP No. 59935V107 | Page 12 of 13 |
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Dated: September 19, 2022
| Venrock Healthcare Capital Partners III, L.P. | ||
| By: | VHCP Management III, LLC | |
| Its: | General Partner | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Co-Investment Holdings III, LLC | ||
| By: | VHCP Management III, LLC | |
| Its: | Manager | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Management III, LLC | ||
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| Venrock Healthcare Capital Partners EG, L.P. | ||
| By: | VHCP Management EG, LLC | |
| Its: | General Partner | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Management EG, LLC | ||
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| Nimish Shah | ||
| /s/ David L. Stepp | ||
| David L. Stepp, Attorney-in-fact | ||
| Bong Koh | ||
| /s/ David L. Stepp | ||
| David L. Stepp, Attorney-in-fact | ||
| CUSIP No. 59935V107 | Page 13 of 13 |
EXHIBITS
| A: | Joint Filing Agreement |
| B: | Power of Attorney for Nimish Shah (incorporated by reference to Exhibit B to Schedule 13G filed February 14, 2020) |
| C: | Power of Attorney for Bong Koh (incorporated by reference to Exhibit C to Schedule 13G filed February 14, 2020) |
EXHIBIT A
JOINT FILING AGREEMENT
In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Shares of Milestone Pharmaceuticals Inc. and further agree that this agreement be included as an exhibit to such filing. Each party to the agreement expressly authorizes each other party to file on its behalf any and all amendments to such statement. Each party to this agreement agrees that this joint filing agreement may be signed in counterparts.
In evidence whereof, the undersigned have caused this Agreement to be executed on their behalf this 19th day of September, 2022.
| Venrock Healthcare Capital Partners III, L.P. | ||
| By: | VHCP Management III, LLC | |
| Its: | General Partner | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Co-Investment Holdings III, LLC | ||
| By: | VHCP Management III, LLC | |
| Its: | Manager | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Management III, LLC | ||
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| Venrock Healthcare Capital Partners EG, L.P. | ||
| By: | VHCP Management EG, LLC | |
| Its: | General Partner | |
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| VHCP Management EG, LLC | ||
| By: | /s/ David L. Stepp | |
| Name: David L. Stepp | ||
| Its: Authorized Signatory | ||
| Nimish Shah | ||
| /s/ David L. Stepp | ||
| David L. Stepp, Attorney-in-fact | ||
| Bong Koh | ||
| /s/ David L. Stepp | ||
| David L. Stepp, Attorney-in-fact | ||