Sec Form 4 Filing - FRIEDBERG ALBERT @ VACCINEX, INC. - 2024-11-14

FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person FRIEDBERG ALBERT 2. Issuer Name and Ticker or Trading Symbol VACCINEX, INC. [ VCNX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) X __ Director X __ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 220 BAY STREET, SUITE 600 3. Date of Earliest Transaction (MM/DD/YY) 11/14/2024 (Street) TORONTO, A6M5J 2W4 4. If Amendment, Date Original Filed (MM/DD/YY) 6. Individual or Joint/Group Filing (Check Applicable Line) _____ Form filed by One Reporting Person __ X __ Form filed by More than One Reporting Person (City) (State) (Zip)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security (Instr. 3) 2. Transaction Date (MM/DD/YY) 2A. Deemed Execution Date, if any (MM/DD/YY) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 2,094 D Common Stock 180 I By Pan Atlantic Holdings Ltd. ( 1 ) Common Stock 16,724 I By Friedberg Global-Macro Hedge Fund Ltd. ( 2 ) Common Stock 11/14/2024 A 30,756 A $ 3.25 1,051,389 I By FCMI Parent Co. ( 3 )

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities) 1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (MM/DD/YY) 3A. Deemed Execution Date, if any (MM/DD/YY) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) 6. Date Exercisable and Expiration Date (MM/DD/YY) 7. Title and Amount of Underlying Securities (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Owne rship Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4) Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares Warrant (Right to Buy) $ 0.0001 11/14/2024 A 584,646 ( 4 ) ( 4 ) Common Stock 584,646 $ 3.2499 584,646 I By FCMI Parent Co. ( 3 ) Warrant (Right to Buy) $ 5.636 09/18/2024 09/18/2029 Common Stock 653,210 653,210 I By FCMI Parent Co. ( 3 ) Warrant (Right to Buy) $ 0.0001 ( 4 ) ( 4 ) Common Stock 102,960 102,960 I By FCMI Parent Co. ( 3 ) Warrant (Right to Buy) $ 0.0001 ( 4 ) ( 4 ) Common Stock 92,504 92,504 I By FCMI Parent Co. ( 3 )

Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other FRIEDBERG ALBERT 220 BAY STREET SUITE 600 TORONTO, A6M5J 2W4 X X FCMI Parent Co. 220 BAY STREET SUITE 600 TORONTO, A6M5J 2W4 X Signatures /s/ Jill Sanchez, Attorney-in-Fact for Albert Friedberg 11/18/2024 Signature of Reporting Person Date FCMI Parent Co. By: /s/ Dan Scheiner, Vice President 11/18/2024 Signature of Reporting Person Date

Explanation of Responses:

( 1 )Mr. Friedberg is the majority owner of Pan Atlantic Holdings Ltd. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 2 )Mr. Friedberg possesses voting and dispositive power over the reported securities and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 3 )Mr. Friedberg is the majority owner, a director and the president of FCMI Parent Co. ("FCMI") and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. ( 4 )These pre-funded warrants are currently exercisable, subject to a 39.99% beneficial ownership limitation on the reporting persons, at an initial exercise price of $0.0001 and will expire on the date they are exercised in full.

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

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